1. Scrip
  2. >>R&D
  3. >>Clinical Trials

Takeda Charges Into Diversification With ITP Win

Results Further Long-Term Strategy

 
• By Alaric DeArment

The company announced positive topline results from a Phase II study of mezagitamab and expects to have five programs in Phase III development this fiscal year.

• Source: Shutterstock

With positive topline Phase II results and plans to move it into Phase III development, Takeda Pharmaceutical Co. Ltd.’s mezagitamab joins the drug maker’s list of Phase III-ready assets that together provide a glimpse of its diversified development strategy.

The Japanese drug maker announced 13 March that the randomized, placebo-controlled Phase II study of mezagitamab (TAK-079) showed positive safety and efficacy results among patients with persistent or chronic primary immune thrombocytopenia (ITP), and that the company plans to start a Phase III trial during its 2024 fiscal year, which lasts from

Key Takeaways

  • Takeda announced positive topline results from a Phase II study of mezagitamab in persistent or chronic immune thrombocytopenia and plans to launch a Phase III trial of the drug.

  • The drug maker estimates an addressable patient population of about 40,000-50,000 patients across major markets in North America, Europe and Asia

Read the full article – start your free trial today!

Join thousands of industry professionals who rely on Scrip for daily insights

  • Start your 7-day free trial
  • Explore trusted news, analysis, and insights
  • Access comprehensive global coverage
  • Enjoy instant access – no credit card required
Start Free Trial

Already a subscriber?

More from Clinical Trials

Insilico Fast-Tracks First AI-Designed TNIK Inhibitor Into Phase III For IPF

 
• By Dexter Jie Yan

InSilico will leapfrog Phase IIb to progress its AI-generated candidate for idiopathic pulmonary fibrosis directly into a Phase III trial in China, as it prepares for an IPO in Hong Kong.

Pipeline Watch: Six Approvals And Thirteen Phase III Readouts

Pipeline Watch is a weekly snapshot of selected late-stage clinical trial events and approvals announced by pharmaceutical and biotech companies at medical and industry conferences, in financial and company presentations, and in company releases and statements.

Viatris Will File ‘Fast-Acting’ Meloxicam For FDA Approval This Year

 
• By Joseph Haas

Seven years after acquiring it, Viatris will seek approval of a meloxicam formulation for acute pain backed by data from two Phase III studies in post-surgical pain settings.

CRISPR Therapeutics Unveils Promising Early In Vivo Cholesterol-Lowering Results

 
• By Andrew McConaghie

The Phase I results are the best to date among ANGPTL3-targeting candidates in the pipeline, but analysts will wait for further updates before predicting a likely winner.

More from R&D

Sanofi R&D Head’s Words Of Wisdom For Biotechs

 
• By Kevin Grogan

Houman Ashrafian tells delegates at Swiss Biotech Day that ‘literally only two things matter in our industry – target credentialing and differentiated pharmacology. The rest is execution.’

Marea Eyes Cardioprotective Benefit With ANGPTL4 Inhibition

 
• By Joseph Haas

Phase IIa data for ANGPTL4-targeted antibody shows reduced triglycerides and remnant cholesterol, which Marea asserts indicates potential to protect against cardiovascular outcomes.

First Win For AstraZeneca’s Enhertu In Early-Stage Breast Cancer Treatment

 
• By Andrew McConaghie

Already dominating in later lines of breast cancer treatment, Enhertu could now displace both chemotherapy combinations and Roche’s Kadcyla in early-stage HER2-positive patients.