Fabhalta IgAN Nod Plays Into Novartis’s Long-Term Nephrology Development Plan

US FDA approval in IgAN is just the first step in a much larger renal disease strategy for the company, which includes additional kidney indications for Fabhalta.

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Novartis AG has developed a new kidney disease field team to help market Fabhalta (iptacopan) for primary immunoglobulin A nephropathy (IgAN) while relying on its existing hematology infrastructure to market the drug for paroxysmal nocturnal hemoglobinuria (PNH), with an eye toward developing a large nephrology franchise in the coming years.

The US Food and Drug Administration granted accelerated approval to Fabhalta for reducing proteinuria in adults with IgAN and at risk of rapid disease progression on 7 August

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