Two of the most formative experiences I gained working as the commercial person within pharmaceutical development teams involved the inability to predict either the absence of patients or the absence of a viable market for products under development.
Stock Watch: When Development Goes Too Far
Beware R&D Organizations With Unfettered Access To Clinical Trial Budgets
R&D managers can sometimes drive a drug’s development despite evidence of its unviability. This has recently resulted in a scramble to adjust in-progress trial protocol and post-approval cost-effectiveness concerns.

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