Sanofi RIPK1 Drug Receives Last Rites

The French major and partner Denali's attempts to validate RIPK1 as a promising target have once again foundered as oditrasertib comes up short in a multiple sclerosis trial months after a failure in amyotrophic lateral sclerosis.

Sanofi
• Source: Getty

Sanofi's multiple sclerosis pipeline, which has shown promise of late, has suffered a setback with the news that oditrasertib, partnered with Denali Therapeutics Inc., has failed in a mid-stage study.

The demise of oditrasertib, formerly known as SAR443820/DNL788, was revealed by Denali in a brief US Securities and Exchange Commission...

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