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AstraZeneca Tries Plan B For Dato-DXd After Regulator Feedback

 
• By Andrew McConaghie

The FDA has indicated that the antibody-drug conjugate looks more promising in a subgroup of EGFR mutated lung cancer patients and AstraZeneca has refiled accordingly.

AstraZeneca and partner Daiichi Sankyo have unveiled a major change of plan for the first filing of their closely-watched lung cancer therapy datopotamab deruxtecan (Dato- DXd).

The companies filed Dato-DXd with the US Food and Drug Administration for patients with advanced or metastatic nonsquamous non-small cell...

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