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Janux Has A License To Thrill With 007’s Prostate Cancer Results

 
• By Andrew McConaghie

The masked T-cell engager has produced eye-catching results in heavily pre-treated prostate cancer patients, and Janux is aiming to jump ahead of Novartis’s Pluvicto in treatment regimens.

Prostate cancer
CellCentric says it has a first-in-class prostate cancer therapy • Source: Shutterstock

Janux Therapeutics has generated great excitement with its prostate cancer treatment, JANX007, with analysts hailing updated Phase I results as showing potential best-in-class safety and efficacy.

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Novotech CEO On Flexible Trial Solutions Amid Tariff, Geopolitical Tensions

 
• By Anju Ghangurde

Novotech's CEO talks about rising interest for trials in regions with “regulatory agility” and “strategic insulation” from geopolitical complexity, especially among emerging and mid-sized biotech sponsors. Operational "reassessment” among some sponsors on exposure to China-based CROs/CRDMOs is another area he discussed.

Akeso Wins US Approval For PD-1 Antibody In NPC, Partly On US Data

 
• By Dexter Jie Yan

Akeso’s penpulimab will be the second to hit the US market for nasopharyngeal carcinoma, but the first to win FDA approval for the indication based on clinical findings in US patients.

In Brief: Bioxodes To Take Novel Hemorrhagic Stroke Drug Into Registrational Trial

 
• By Sushmita Panda

The Belgium-based firm will take the first-in-class drug, based on tick saliva, targets inflammation without increasing bleeding, into a Phase IIb trial is in preparation, supported by a new series B funding round.

Sanofi Spends Big In US But Offers Crumbs Of Comfort For Europe

 
• By Kevin Grogan

CFO François Roger tells Scrip the French drugmaker is flexible geographically on making investments but its spend in the US has risen regardless of the threat of tariffs.

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