Once a key part of its next-generation plans in cancer, Merck & Co. has called a halt to the last remaining Phase III studies of its TIGIT- and LAG-3 targeting immunotherapy assets.
Merck & Co. Calls Time On Flop TIGIT And LAG-3 Programs
After investing heavily in both mechanisms for IO-IO combinations, Merck is cutting its losses with vibostolimab and favezelimab, and switching its anticancer bets to other modalities.

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Pipeline Watch is a weekly snapshot of selected late-stage clinical trial events and approvals announced by pharmaceutical and biotech companies at medical and industry conferences, in financial and company presentations, and in company releases and statements.
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