Merck Gets Closer To Extending Keytruda Franchise With Subcutaneous Version

Merck expects Keytruda to come under Medicare price controls in 2028, but an analyst said the subcutaneous version could shield revenues for the franchise.

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Merck & Co. is awaiting regulatory approvals for its subcutaneous version of PD-1 inhibitor pembrolizumab, and its successful head-to-head trial against the original intravenous Keytruda (pembrolizumab) quantifies the convenience advantages. But while that may help to mitigate anticipated price controls under the Inflation Reduction Act, biosimilars of Keytruda will likely still present strong competition.

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