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EuroPCR 2017: Boston Scientific's Lotus TAVR Beats Medtronic's CoreValve In REPRISE III, But Pacemaker Issue Remains

 
• By Reed Miller

Boston Scientific's repositionable, mechanically expanded Lotus transcatheter aortic valve performed better than Medtronic's CoreValve for the primary composite effectiveness endpoint in the REPRISE III trial, according to results presented at the EuroPCR meeting in Paris. But the Lotus patients in the trial were more likely to need a pacemaker than the CoreValve patients, a risk that investigators believe can be mitigated with better operator technique.

REPRISE III, the largest randomized, head-to-head comparison of two transcatheter valves, has reassured Boston Scientific Corp. that its Lotus repositionable, mechanically expanded transcatheter aortic valve will be able to compete with the more established TAVR systems once it reaches the market.

Ted E. Feldman of the NorthShore University HealthSystem in Evanston, Illinois presented one-year results from the global, multi-center trial at the the EuroPCR Scientific Program in Paris on May 16

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