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Starts & Stops: Corlife's Decellularized Human Pulmonary Valve Shows Early Promise

 
• By Reed Miller

Starts & Stops is a regular feature highlighting Medtech Insight editors' picks of noteworthy medtech clinical trial initiations, completions and suspensions each month. News about trials of cardiovascular devices, especially novel heart valve replacement technologies, lead this month's edition, covering mid-May through mid-June.

Clinical Trial
• Source: shutterstock.com

Three years after it was initiated, the 121-patient ESPOIR trial of Corlife's Espoir PV decellularized human pulmonary valve has just released its early results and they prove to be very promising so far.

Hanover, Germany-based Corlife is one of several companies trying to develop "living" heart valves that help the heart create a functional valve out of the patient's own cells rather than animal tissue valves that wears out or mechanical valves that are prone to thrombosis. (Also see "Valve Experts: Tissue Engineering Can Solve Mechanical/Tissue Dilemma" - Medtech Insight, 22 December, 2008.) For example, Xeltis AG is developing a bioabsorbable polymer matrix valve that creates a scaffold for a new valve to grow

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More from R&D

No Knife, No Burn, Just Bubbles: HistoSonics Hits 90% Tumor Control In #HOPE4Liver Trial, Eyes IPO Timing

 
• By Marion Webb

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• By Brian Bossetta

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