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UCB Pushes On With Potential Myasthenia Gravis Therapy, But Competition Looms

 
• By John Davis

The anti-FcRn MAb, rozanolixizumab, has been found to be effective in myasthenia gravis and has potential in ITP, but other companies are also developing potential therapeutic candidates for such auto-immune conditions.  

Acceleration
The development of rozanolixizumab is to be accelerated. • Source: Shutterstock

UCB SA is planning to start a confirmatory clinical study of its novel subcutaneously administered anti-FcRn antibody, rozanolixizumab, in the auto-immune disorder myasthenia gravis in the second half of 2019, after finding the MAb was associated with positive clinical benefits in a Phase II proof-of-concept study in the condition.

The Brussels, Belgium-based multinational is striving to best other companies keen to develop new therapies for myasthenia gravis, a condition characterized by skeletal muscle weakness related to the presence of auto-antibodies

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