Can COMPASS Bring Psilocybin’s ‘Magic’ To Depression?

COMPASS Pathways Hopes To Market its Psilocybin Capsule By 2025

COMPASS is testing a synthetic form of psilocybin, the active “magic mushroom” ingredient, in long-term depression patients, and thinks the capsule can be approved by 2025, its co-founder tells Scrip.

Mushrooms_Brain
UK-Based group’s psilocybin therapy has fast track status • Source: Shutterstock

COMPASS Pathways believes it has found a viable, mind-altering therapy for treating long-term depression: a synthetic form of psilocybin now in Phase IIb trials which, if successful, could surmount current legal barriers and stigma associated with psychedelic substances, the company’s co-founder and chief innovation officer told Scrip.

A big step towards that goal was achieved this year in a placebo-controlled Phase I study evaluating COMP360 (psilocybin) in healthy volunteers, and

Read the full article – start your free trial today!

Join thousands of industry professionals who rely on Scrip for daily insights

  • Start your 7-day free trial
  • Explore trusted news, analysis, and insights
  • Access comprehensive global coverage
  • Enjoy instant access – no credit card required

More from Neurological

Viatris Will File ‘Fast-Acting’ Meloxicam For FDA Approval This Year

 
• By 

Seven years after acquiring it, Viatris will seek approval of a meloxicam formulation for acute pain backed by data from two Phase III studies in post-surgical pain settings.

Lilly And Alchemab Tap Into Resilient Individuals To Develop ALS Drug

 

The pharma company is helping to validate the biotech’s model by developing a novel amyotrophic lateral sclerosis candidate, based on its novel approach that ‘turns drug discovery on its head’.

Accelerated Approval May Be Out Of Reach For PTC’s Huntington’s Drug

 
• By 

PTC said its updated Phase II data for PTC 518 met the primary endpoint of Huntingtin’s protein reduction, but analysts said there isn’t clear correlation with clinical benefit.

In Brief: Ferrer Signs Deal For Prilenia’s Pridopidine In Europe

 

The companies will co-develop the drug for additional indications beyond Huntington’s disease, while Prilenia retains rights in key global markets.

More from Therapy Areas