Dazodalibep Expands Horizons With Phase II Sjögren’s Syndrome Data

A Phase II trial of the anti-CD40 drug, which Horizon Therapeutics acquired in early 2021, met its primary endpoint in Sjögren’s, showing potential utility across multiple autoimmune indications.

Horizon unveiled positive Phase II data for dazodalibep in Sjögren’s syndrome • Source: Shutterstock

Horizon Therapeutics plc’s acquisition of Viela Bio in early 2021 is showing signs of paying off as one of the key assets in that acquisition, dazodalibep, produced positive results in a Phase II study in Sjögren’s syndrome (SS).

The company announced 12 September that the Phase II trial, in SS patients with moderate-to-high systemic disease activity, met its...

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