Data At ASCO From J&J Zytiga Trial’s Early End = Intel For Medivation’s MDV3100 Program

Details from the COU-302 trial of Johnson & Johnson’s Zytiga, stopped early for efficacy in March, were released at the American Society of Clinical Oncology meeting, revealing to Medivation/Astellas insights on how to tweak their ongoing registrational trial for enzalutamide (MDV3100) in the pre-chemo prostate cancer space.

Medivation Inc./Astellas Pharma Inc. have been handed an opportunity to sharpen up the regulatory strategy for their prostate cancer drug enzalutamide (MDV3100) after data from the Phase III COUGAR-302 trial, testing Johnson & Johnson’s Zytiga (abiraterone) in pre-chemotherapy patients, were revealed at the American Society of Clinical Oncology meeting in Chicago.

The Zytiga trial was stopped in March after an interim analysis showed significant improvement in radiological progression-free survival for the...

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