Role Of Cost And Evidence In Value-Based Purchasing Highlighted By Zaltrap Price Adjustment

Sanofi’s recent reduction of the Zaltrap price after the Memorial Sloan-Kettering Cancer Center said it would not provide the drug to its advanced colorectal cancer patients due to its high cost relative to Avastin highlights the role cost and available clinical evidence will have as payers make value-based purchasing decisions.

As concepts such as accountable care organizations and value-based insurance design gain traction as instruments to help contain health care costs, cost as a function of value is going to receive greater attention. The recent public discourse over the pricing of Sanofi/Regeneron Pharmaceuticals Inc.’sZaltrap (ziv-aflibercept) and Memorial Sloan Kettering Cancer Center’s decision not to offer it to its advanced colorectal cancer patients offers a preview of how value-based decisions that include cost in the overall value equation could be made.

The Zaltrap example suggests a couple of lessons relative to value-based purchasing: first, that a private payer with significant clout can cite evidence of a product’s lack of clinical superiority relative to a competitor to get a discounted price and second, that payers are forging

Read the full article – start your free trial today!

Join thousands of industry professionals who rely on Pink Sheet for daily insights

  • Start your 7-day free trial
  • Explore trusted news, analysis, and insights
  • Access comprehensive global coverage
  • Enjoy instant access – no credit card required

More from United States

More from North America

Most Favored Nation Policy ‘Lazy, Misguided,’ But US Price Reforms Politically ‘Inevitable’

 
• By 

Policy experts and pharma executives react to President Trump’s executive order on “equalizing” drug prices between the US and comparable nations at the ISPOR 2025 conference.

New Guidance Suggests SubQ Keytruda, Opdivo Formulations May Not Avoid Medicare Negotiations

 

New draft guidance on the third cycle of Medicare drug price negotiations goes against Merck and BMS expectations for their cancer drugs. The guidance also tackles Part B and renegotiated prices for the first time.

Mayne’s Nextstellis Promo Wrong To Suggest Better Safety Than Other Contraceptives, FDA Says

 
• By 

A professional slide deck for the drospirenone/estetrol oral contraceptive inappropriately suggests it is safer than other estrogen-containing products and understates risks, Office of Prescription Drug Promotion said in the first “untitled” letter issued since reductions-in-force.