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Shire’s ViroPharma Purchase Aims To Build Rare Disease Giant

 
• By Sten Stovall

Shire is buying ViroPharma at a steep premium to acquire its pipeline assets, notably C1 esterase inhibitor Cinryze, which the London-listed specialty pharma plans to expand internationally, initially to treat hereditary angioedema and later for other rare diseases.

Lured by ViroPharma Inc.’s successful Cinryze (C-1 esterase inhibitor (human)) treatment for hereditary angioedema, a genetic immune disorder, Ireland-based Shire PLC has agreed to pay some $4.2 billion cash to acquire the U.S. group and marry its rare disease pipeline potential with that of Shire’s.

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