One Difference Between Amylyx’s ALS Drug And Aduhelm: A Biomarker Endpoint

US FDA’s Billy Dunn says that if the drug had shown a positive effect on plasma neurofilament heavy chain, it ‘would have provided important contextual and supportive information of an ostensibly beneficial effect on the clinical measure.’

ALS
Biomarker data could have helped show efficacy of Amylyx's ALS drug AMX0035 • Source: Alamy

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