Japan Eases Local Clinical Data Requirements For Rare Disease Drug Filings

Japan is cautiously easing Japanese clinical data requirements for rare disease drugs to allow faster and more flexible approvals, including on a conditional basis supported by postmarketing studies.

Japan has cautiously eased regulatory requirements related to novel drugs for rare diseases, with the Ministry of Health, Labour and Welfare (MHLW) to allow approval filings without data from Japanese clinical trials under certain conditions.

At the same time, the ministry has also expanded flexibilities around a related conditional approval scheme

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