Janssen Looks To Differentiate Anticoagulant Xarelto With Broad Label

With positive data now in for Xarelto’s ability to treat and prevention recurrence of VTE, Janssen looks to file for a fourth indication for the novel anticoagulant, positioning the drug to crack a promising market that may be under-appreciated.

Johnson & Johnson subsidiary Janssen Inc. believes that its oral anticoagulant Xarelto (rivaroxaban) is on its way to having the broadest label of any of the novel anticoagulant agents.

With positive findings in treatment of symptomatic pulmonary embolism and prevention of recurrent events from the EINSTEIN-PE trial, it may be the first to crack an important indication that, until now, has been under the radar. The EINSTEIN-PE trial showed non-inferior efficacy for Xarelto and a 50% reduction in major bleeding compared to the standard of care

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