Pazdur’s Tale Of Two Targeted Therapies

FDA’s oncology office director suggests Ariad’s ponatinib and ChemGenex’s Omapro represent the best and worst of times, respectively, in the quality of development programs for personalized medicines.

Offering his own version of Charles Dickens’ “A Tale of Two Cities,” FDA Office of Hematology and Oncology Products Director Richard Pazdur highlighted two real-world examples representing the best and worst of times in the quality of development programs for personalized cancer medicines.

Both therapies cited by Pazdur at a Sept. 14 conference on drug/diagnostic co-development are targeted at patients with chronic myelogenous...

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