With New Mechanism, Can Eisai’s Fycompa Make Its Mark In Epilepsy?

Efficacy results were not uniformly positive in pivotal trials of newly approved perampanel, but FDA explains that may be due to high placebo rates in some international sites.

Eisai Co. Ltd.’s Fycompa (perampanel) is only the second drug with a new mechanism of action approved for epilepsy in the last decade. Now the drug needs to find its place in clinical practice amid many treatment options, including generics.

FDA approved the once-daily AMPA-type glutamate antagonist as an add-on therapy for partial onset seizures with or without secondarily generalized...

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