End-Of-Life-Considerations Fail To Save Lilly’s Alimta For NSCLC At NICE

Britain’s NICE has rejected Eli Lilly’s Alimta for non-small-cell lung cancer, citing cost-effectiveness issues. But the US drug maker still has options to get the drug approved by the pricing watchdog.

The UK’s reimbursement watchdog has decided against recommending Eli Lilly & Co.’s Alimta (pemetrexed) for uptake into the publicly-funded NHS for maintenance treatment of non-small-cell lung cancer (NSCLC). While cost effectiveness considerations were behind the preliminary rejection, the decision of Feb. 22 raises concerns about the appropriateness and purpose of NICE’s end-of-life criteria.

As far as the clinical effectiveness of Alimta goes, NICE likes what it sees and already knows quite a bit...

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