Taranabant and Rimonabant: Same Class, Same Risk?

After an increased risk of suicidality led to the demise of Sanofi-Aventis' rimonabant (Zimulti), another drug in the same class of cannabinoid-1 receptor blockers (Merck's taranabant) is showing a similar signal in Phase III trials. Merck has vowed to push ahead with an NDA filing.