Lumicell’s Cancer Imaging Drug Faces Clinical Meaningfulness, Anaphylaxis Risk Questions At FDA Panel

US FDA advisory committee briefing documents say drug-device combo Lumisight (pegulicianine) is effective at picking up cancer but it is not clear whether that translates to patient benefit.

two people in operating room performing surgery
Lumicell hopes to help breast cancer patients avoid a second surgery with its medical imaging drug. • Source: Shutterstock

Lumicell Inc.’s breast cancer imaging drug met its mark in its pivotal study, the US Food and Drug Administration said ahead of an advisory committee review, but the agency is not clear whether that mark represents a meaningful benefit to patients.

The mixed efficacy review, combined with safety concerns, could make for a challenging advisory panel for the sponsor on 5...

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