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AstraZeneca’s Farxiga Label Includes, But Downplays, Bladder Cancer Risk

 
• By Emily Hayes

AstraZeneca’s SGLT-2 inhibitor Farxiga (dapagliflozin) finally clears FDA, and without a black box warning on bladder cancer risk – allowing the drug to compete with J&J’s first-to-market Invokana.

FDA did include the potential bladder cancer risk in labeling for AstraZeneca PLC/Bristol-Myers Squibb Co.’s diabetes drug Farxiga (dapagliflozin), but in a way that should have limited impact on the drug’s competitive prospects.

A member of the new class of sodium glucose cotransporter-2 (SGLT-2) inhibitors for diabetes, which act by clearing glucose in...

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