Lilly Rejects NICE Comparator For Efient In ACS, But Gains Approval Anyway

Despite Lilly's decision not to make an indirect comparison its chosen comparator, AstraZeneca’s Brilinta, NICE agrees that Lilly's Efient is cost-effective and sometimes clinically superior to standard care.

The U.K.’s National Institute for Health and Clinical and Clinical Excellence has agreed to support reimbursement for Eli Lilly & Co.'s Efient (prasugrel) for acute coronary syndrome – a widening of a currently restricted label – even though Lilly declined NICE’s recommendation to compare the drug with AstraZeneca PLC's Brilinta.

Generally, a manufacturer’s decision not to compare its product with another selected by a European health technology assessment agency such...

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