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Merck Calls It Quits On Anacetrapib

 
• By Mary Jo Laffler and Emily Hayes

Despite success in REVEAL outcomes trial, Merck will not submit the for the cholesteryl ester transfer protein (CETP) inhibitor for regulatory approval.

stopping the Dominio effect

Merck & Co. Inc. is making the prudent choice in opting not to pursue regulatory approval for the CETP inhibitor anacetrapib, avoiding what could have been a tricky review with only the possible reward being entry into the commercial quagmire of the cholesterol market that has hindered uptake of the PCSK9 inhibitor class.

"The decision follows a thorough review of the clinical profile of anacetrapib, including discussions with external experts," the firm said in its Oct. 11 announcement.

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