Opioid Use Disorder: Is Reduced Usage A Better Endpoint Than Abstinence?

Some at patient-focused drug development meeting argue that cutting opioid use should not be considered treatment failure and that medications allowing controlled opioid use may be beneficial.

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Patients are encouraging the US FDA to consider treatments allowing control or management of opioid use, rather than seeking complete abstinence, may be a laudable goal for opioid use disorder.

A significant portion of FDA's April 17 patient-focused drug development meeting on opioid use disorder included discussion of potential medications not designed to achieve abstinence from opioid use

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