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Stand-Off: Vertex Refuses NICE Data on CF Drug Symkevi, HTA Body Awaits Next Move

 
• By Sten Stovall

Vertex says it will not file data on its cystic fibrosis drug Symkevi (tezacaftor/ivacaftor) until the UK's NICE changes the way it assesses drugs.

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Who will make the next move in the Vertex/NICE standoff? • Source: Shutterstock

In a dramatic stand-off, Vertex Pharmaceuticals Inc. is refusing to file data with the UK's National Institute for Health and Care Excellence for its latest combination therapy Symkevi (tezacaftor / ivacaftor) until NICE changes how it assesses the cost-effectiveness of its drug.

NICE in turn has suspended its appraisal of the product, saying it will not move on the issue and that...

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