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CAR-T Funding: It's (Nearly) All About The Price In The UK

 
• By Ian Schofield

Gilead’s Yescarta and Novartis’s Kymriah are pioneering and effective approaches to the treatment of serious cancers, but in the UK they have had mixed fortunes at the hands of NICE, the body that decides whether new therapies are value for money and should be available under the national health service. Both companies will probably have to cut their asking price to secure routine funding

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NICE is considering its final recommendation on routine CAR-T funding

The two CAR-T therapies, Gilead Sciences Inc.’s Yescarta (axicabtagene ciloleucel) and Novartis AG’s Kymriah (tisagenlecleucel), have both been rejected for routine funding on the National Health Service in preliminary guidance from the UK's National Institute for Health and Care Excellence on cost-effectiveness grounds. But that’s not the end of the story. 

NICE is impressed with the clinical performance of Yescarta and Kymriah, and has recommended them for provisional NHS coverage under...

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