New Package Leaflets Needed For EU Drugs With Ethanol Excipient

Changes Needed To Explain Potential Effects In Children

New EU guidance has been issued to help sponsors update the package leaflets of medicines that contain ethanol as an excipient to better convey warnings of potential effects in children.

Doctor examining leaflet
Product Info For Medicines With Ethanol Will Have To Be Updated • Source: Shutterstock

The European Medicines Agency has issued guidance on the information that companies should include in the package leaflet of medicines that use ethanol as an excipient to explain the potential effects of the substance in children. Sponsors of affected medicines have three years to update their product information.

Ethanol may be used as a solvent, preservative or a cutaneous penetration enhancer in medicines. Although human exposure to ethanol...

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