Same Price & Trial Data: Scotland OKs Spravato Funding After England Says No

Discrepancy in access to Janssen’s antidepressant nasal spray between patients in Scotland and those in England and the rest of the UK may be due to the differences in methodologies and approaches used by the health technology assessment bodies.

Scotland
Janssen's depression spray will be made available on NHS Scotland • Source: Shutterstock

The health technology assessment (HTA) body in Scotland has accepted Janssen Pharmaceuticals’s Spravato (esketamine), after deciding that the first-of-a-kind nasal spray for difficult-to-treat depression is an acceptable use of the country’s National Health Service resources.

The advice by the Scottish Medicines Consortium that Spravato should be made available on NHS Scotland for adults with severe treatment-resistant depression (TRD) was announced on 7 September. It contrasts sharply with last week’s draft recommendation by the UK HTA body, NICE, which for the second time rejected Spravato for use on England’s NHS for the same indication, because of uncertainties over the product's clinical and cost effectiveness

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