Sayonara, Yamagata: US Seasonal Flu Vaccines Shift From Quadrivalent To Trivalent For 2024-2025

New US formulations will contain only one B virus antigen after shedding the B/Yamagata component, a strain that has not been detected in circulation since March 2020. However, some US manufacturers will continue to produce quadrivalent vaccine for use in other countries, which have been slower to transition to trivalent.

Car wheels
Wheels are in motion for a global change to trivalent seasonal flu vaccine, with the US leading the way. • Source: Shutterstock

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