Another CAR-T First: Yescarta Wins Lymphoma Funding In England

Gilead has agreed a confidential deal with NHS England under which its pioneering CAR-T therapy Yescarta will be provided to adult lymphoma patients under the Cancer Drugs Fund. The funding decision gives Yescarta an edge in the lymphoma market over Kymriah, the other EU-authorized CAR-T treatment.

Chimeric antigen receptor
Yescarta helps the body's T cells attack cancer • Source: Shutterstock

Gilead Sciences Inc.’s Yescarta (axicabtagene ciloleucel) has become the first CAR-T cell therapy to be funded for use in adults in the UK after the company reached a confidential deal with the National Health Service. The pioneering therapy will be paid for by the UK Cancer Drugs Fund for patients with lymphoma.

Up to 200 adult patients a year will receive the one-off, potentially curative treatment under what NHS England described as “the first negotiated deal of its kind struck in Europe

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