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Breast Cancer Study Finds Benefit From Aspirin Use Linked To DNA Profiles

 
• By Eileen Francis

Breast cancer mortality among women who regularly used aspirin decreased 22%-40% for those with unmethylated tumor promoter and progesterone receptor genes, while women with methylated tumor promoter had of 67% all-cause death risk, study finds. Researchers and editorial author say study underscores importance of looking at methylation profiles, or chemical changes, in tumor tissue DNA.

Woman's hand pours the medicine pills out of the bottle - Image

A history of regular aspirin use could be linked to a significantly lower breast cancer mortality for women with certain DNA characteristics, though it could conversely increase mortality in women with other DNA features, according to a study by University of North Carolina researchers.

Published in the American Cancer Society's Cancer journal, the observational study with data from 1,266 women with breast cancer – including 301 who took aspirin at least once a week...

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