A maximal usage trial (MUsT) conducted by FDA researchers demonstrates that sunscreen active ingredients can penetrate skin to reach the bloodstream at higher levels than previously believed.
FDA MUsT Shows Sunscreen Ingredient Absorption ‘Not Just A Theoretical Concern’
In FDA’s maximal usage trial published May 6 in JAMA, oxybenzone, octocrylene, avobenzone and ecamsule all absorbed into subjects’ bloodstreams at levels that raise systemic safety questions. The active ingredients are among 12 that FDA identified in a February proposed rule as currently lacking data to support continued GRASE status.
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Fragrance Creators Association will push the Trump Administration to exclude from tariffs fragrance materials that cannot be produced or cultivated domestically, while both FCA and the Personal Care Products Council will continue to promote the economic benefits of their respective industries.
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Personal care companies selling in California that suspect they are subject to its listing of a common stabilizer and packaging material should collect Certificates of Analysis for all raw materials, pursue third-party formula testing and retain counsel.
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Preliminary registration data released by FDA offers a first glimpse of the Modernization of Cosmetics Regulation Act’s impact on information the agency has at hand.